Analysis Software
Data produced by or submitted to GeneQuest for review may be analyzed on numerous validated software platforms. Depending on the informative value and complexity of the data, GeneQuest will interrogate each run on the most reliable and up-to-date software genotyping platforms.
BulletProof™
Continuous (Bayesian) probabilistic software developed by the European DNA (eDNA) Consortium allows for a Frequentist and MCMC modeling of simple and complex mixtures and provides for mixture deconvolution.
GeneMapper ID-X Software v1.6
GeneMapper® ID-X v1.6 software is an automated genotyping software solution for all data analysis needs, including forensic casework, databasing, and paternity testing.Read More →
GeneMapper®
ID-X Software supports a multi-user database configuration and provides a set of data analysis and sample review tools that streamline sizing, allele calling, mixture analysis, and statistical calculations. ID-X v1.6 incorporates a mixture analysis tool which is capable of determining the number of contributors to a mixture and efficiently manage the resulting possible genotypes. This enables the forensic analyst to interpret mixtures and generate accurate statistical calculations.
To learn more about GeneMapper ID-X Software v1.6 please visit LifeTechnologies.com.
GeneMarker HID™
GeneMarker® HID is concordant with GeneMapper®ID and GeneMapper®IDX and compatible with ABI®PRISM 310, 3100, 3130, 3730, 3500 CE output (.fsa, .hid) and chemistries (including GlobalFiler™ 6-Dye™, Identifiler®, Minifiler®, PowerPlex®16, PowerPlex®ESI, PowerPlex®Fusion 5 and 6 Dye, Investigator®24Plex, Investigator®DIPplex and SureID® STR chemistries) uses advanced Windows® technology that is intuitive and easy to learn. Read More →
In addition to standard STR analysis, GeneMarker HID software has been optimized to analyse profiles from YSTRs, Low Copy Number LCN samples, ABI’s MiniFiler™ Kit, and replicate sample consensus.
To learn more about GeneMarker HID™ please visit SoftGenetics.com.[/wpex]
Osiris
OSIRIS (Open Source, Independent Review and Interpretation System) is a public domain quality assurance software package that facilitates the assessment of multiplex short tandem repeat (STR) DNA profiles based on laboratory-specific protocols. Read More →
OSIRIS evaluates the raw electrophoresis data contained in an .fsa or .hid file using an independently derived mathematically-based sizing algorithm, and supports ABI capillary analytical platforms and numerous commercially available CODIS-compliant marker kits. OSIRIS searches for peaks by iteratively fitting expected parametric data signatures to the observed data, usually achieving matches with correlations in excess of 0.999. Parametric peak locations are determined with sub-second accuracy and transformed to base pair coordinates. OSIRIS-analyzed sample peaks align within 0.1 base pair of the position within a locus. Thus, in addition to providing reliable and accurate peak analysis, OSIRIS offers two new peak quality measures – fit level and sizing residual.
To learn more about Osiris please contact forensics@ncbi.nlm.nih.gov.
ArmedXpert™
ArmedXpert™ has been validated by multiple accredited forensic laboratories provides as a full-case management analysis software. Read More →
The program computes all mathematically possible SWGDAM complaint genotype combinations (including deconvolution of up to 3-contributor mixtures) loci by loci, that fit individual labs validated thresholds for PH, PHr, proportions, stutter, and stochastic effects. ArmedXpert™ automatically calculates PopStats concordant statistics for generated profiles including Single Source, CPI/CPE and Likelihood ratios, and allows for customized reporting.
To learn more about ArmedExpert™ please contact nichevision.com.
GPS-ibd (FSS-ibd)™
GPS-ibd allows for the rapid construction of familial pedigree hypotheses and the population of full or partial DNA profiles. Statistical comparison, based on Bayes Nets theory, of the hypotheses leads to detailed likelihood ratio results which can be output as formatted template-based reports. The inclusion of a batch profile processor allows GPS-ibd to be linked to a national DNA database for full familial matching against specific pedigree hypotheses and for the results to be ordered by likelihood ratio. This allows GPS-ibd to be used to guide criminal justice investigations as well as play a pivotal role in disaster victim identification (DVI).
TrueAllele® Casework
TrueAllele® Casework genetic calculator (TAGC™) infers genotypes from DNA mixtures containing one, two, three or more unknown contributors.Read More →
The TrueAllele system, written in MATLAB programming language, resolves DNA mixtures into their component genotypes from the evidence data. Comparisons are subsequently made between the inferred evidence genotype(s) and a reference sample to compute a Likelihood Ratio. The TAGC™ processor electronically explores thousands of parameters, while considering different genotype scenarios, and uploads genotype answers to the TrueAllele database.
To learn more about TrueAllele® Casework please visit cybgen.com.
